They will regenerate to the next multiple of 10. If your health and/ or armor is low, remain out of sight of enemies and let it replenish as much as it can.In addition to this, kill enemies with stealth takedowns by pressing behind them.
However, this isn't advisable, but is still an option. Try and take out the commanders without being noticed, as if they are alerted to your presence they will call for reinforcements which will make things a lot harder then they need to be. These can give you between 5 and 80 additional points. This will reduce the chances of enemies being able to hit you. Hold when near a wall and you will be able to lean out and shoot enemies. On ÜBER difficulty enemies hit harder and take more damage than on lower difficulty levels. While there are some challenging sections of the game, it isn't overly difficult. Feel free to play on this difficulty on your first playthrough. In order to earn this trophy, you must complete the game on the hardest difficulty setting, which is ÜBER difficulty.